G.O.A.L

Dina Halegoua‐DeMarzio, Victor Navarro

Liver International, 2025-3

Herbal and dietary supplements (HDS) are being used worldwide at an increasing rate. Mirroring this trend, HDS‐induced liver injury, also…

Dongyang Li, Hanlin Han, Yixin Sun, Huayue Zhang, Ren Yoshitomi, Sunil C. Kaul, Renu Wadhwa

International Journal of Molecular Sciences, 2024-11-14

We investigated the effect of purified withanolides and extracts derived from Ashwagandha on steatosis, the abnormal accumulation of fat that…

Manoj Kumar Vashisth, Junkai Hu, Mingrui Liu, Syed Hussain Basha, Chen Yu, Wenhua Huang

Scientific Reports, 2024-11-13

Alzheimer's disease (AD) is a progressive neurodegenerative disorder marked by cognitive decline, memory impairment, and behavioral alterations. The N-methyl-D-aspartate (NMDA)…

Alex B. Speers, Axel Lozano-Ortiz, Amala Soumyanath

Nutrients, 2024-11-08

Withania somnifera (common name: ashwagandha; WS) is an Ayurvedic botanical that has become popular for its reputed effects on stress…

Sanjiv Kale, Adrian Lopresti, Ravleen Suri, Neha Garg, Deepak Langade

Journal of Psychoactive Drugs, 2024-11-05

This prospective, randomized, placebo-controlled study assessed the effects of Ashwagandha root extract (ARE) on cognition, energy, and mood in adults…

Velan Arumugam, Venugopal Vijayakumar, Arthi Balakrishnan, Rudra B Bhandari, Deenadayalan Boopalan, Ramesh Ponnurangam, Venkateswaran Sankaralingam Thirupathy, Maheshkumar Kuppusamy

EXPLORE, 2024-11-01

Background Ashwagandha (Withania somnifera) is an adaptogenic herb used to prevent and treat psychosomatic disorders. This systematic review and meta-analysis…

Sartaj Jhooty, Paul Barkhaus, Andrew Brown, Javier Mascias Cadavid, Gregory T. Carter, Jesse Crayle, Terry Heiman-Patterson, Xiaoyan Li, Elise Mallon, Christopher Mcdermott, Tasnim Mushannen, Gary Pattee, Dylan Ratner, Paul Wicks, Martina Wiedau, Richard Bedlack

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2024-11

ALSUntangled reviews alternative and off-label treatments on behalf of people with ALS (PALS) who ask about them. Here, we review…

Smita Manjari Panda, null Nandeshwar, Umakanta Tripathy

International Journal of Biological Macromolecules, 2024-10-26

Breast CAncer gene 1 (BRCA1) is an anti-oncogene that helps the cell repair damaged DNA and preserve genetic material. BRCA1…

Nivedita Singh, Anil Kumar Singh

Journal of Biological Engineering, 2024-10-23

Cerebroside sulfotransferase (CST) is considered as therapeutic target for substrate reduction therapy (SRT) for metachromatic leukodystrophy (MLD). The present study…

Azhar M. Elwan, Ibrahim M. Farag, Mohamed M. M. Elnasharty

Toxicology Research, 2024-10

Detoxification is one of the most important liver functions. Therefore, liver is the front line of defense when the biosystem…

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15th Sep 2022