G.O.A.L

Azhar M. Elwan, Ibrahim M. Farag, Mohamed M. M. Elnasharty

Toxicology Research, 2024-10

Detoxification is one of the most important liver functions. Therefore, liver is the front line of defense when the biosystem…

Smita Manjari Panda, null Nandeshwar, Umakanta Tripathy

International Journal of Biological Macromolecules, 2024-10-26

Breast CAncer gene 1 (BRCA1) is an anti-oncogene that helps the cell repair damaged DNA and preserve genetic material. BRCA1…

Fakhruddin Almuzghi, Abubaker Abdelmalik, Maaly Abuhlaiga

Cureus, 2024-10

A 22-year-old healthy Libyan female suffered moderate to severe liver injury following the ingestion of ashwagandha capsules. Following a latency…

Sanjiv Kale, Adrian Lopresti, Ravleen Suri, Neha Garg, Deepak Langade

Journal of Psychoactive Drugs, 2024-11-05

This prospective, randomized, placebo-controlled study assessed the effects of Ashwagandha root extract (ARE) on cognition, energy, and mood in adults…

Manoj Kumar Vashisth, Junkai Hu, Mingrui Liu, Syed Hussain Basha, Chen Yu, Wenhua Huang

Scientific Reports, 2024-11-13

Alzheimer's disease (AD) is a progressive neurodegenerative disorder marked by cognitive decline, memory impairment, and behavioral alterations. The N-methyl-D-aspartate (NMDA)…

Dongyang Li, Hanlin Han, Yixin Sun, Huayue Zhang, Ren Yoshitomi, Sunil C. Kaul, Renu Wadhwa

International Journal of Molecular Sciences, 2024-11-14

We investigated the effect of purified withanolides and extracts derived from Ashwagandha on steatosis, the abnormal accumulation of fat that…

Alex B. Speers, Axel Lozano-Ortiz, Amala Soumyanath

Nutrients, 2024-11-08

Withania somnifera (common name: ashwagandha; WS) is an Ayurvedic botanical that has become popular for its reputed effects on stress…

Nitin Bhagat, Sajjad Salam, Abhinav Garg, Vijayanandhan Venkatesan, Shetty Hardik, Gaganashree H. G, Sumana Kumar, Ritik Kashwani

Nanotechnology Perceptions, 2024-06-22

Background: Oral cancer is a significant health concern with limited effective treatment options. Curcumin, a compound found in turmeric, has…

Nivedita Singh, Anil Kumar Singh

Journal of Biological Engineering, 2024-10-23

Cerebroside sulfotransferase (CST) is considered as therapeutic target for substrate reduction therapy (SRT) for metachromatic leukodystrophy (MLD). The present study…

Velan Arumugam, Venugopal Vijayakumar, Arthi Balakrishnan, Rudra B Bhandari, Deenadayalan Boopalan, Ramesh Ponnurangam, Venkateswaran Sankaralingam Thirupathy, Maheshkumar Kuppusamy

EXPLORE, 2024-11-01

Background Ashwagandha (Withania somnifera) is an adaptogenic herb used to prevent and treat psychosomatic disorders. This systematic review and meta-analysis…

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15th Sep 2022