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31

Enhanced production of withaferin A from the hairy root culture of Withania somnifera via synergistic effect of Methyl jasmonate and β-cyclodextrin

Mahbobeh Karami, Mohammad Reza Naghavi, Jaber Nasiri, Narjes Farzin, Codruta Ignea

Plant physiology and biochemistry: PPB, 2024-02-22

Due to low amounts of withanolides produced in some plants and high demand for various applications, their biotechnological production is…

32

Nutraceuticals known to promote hair growth do not interfere with the inhibitory action of tamoxifen in MCF7, T47D and BT483 breast cancer cell lines

Richard Baker, Giorgio Dell'Acqua, Aleksander Richards, M. Julie Thornton

PloS One, 2024

BACKGROUND: Hair loss/thinning is a common side effect of tamoxifen in estrogen receptor (ER) positive breast cancer therapy. Some nutraceuticals…

33

ALSUntangled #74: Withania Somnifera (Ashwagandha)

Sartaj Jhooty, Paul Barkhaus, Andrew Brown, Javier Mascias Cadavid, Gregory T. Carter, Jesse Crayle, Terry Heiman-Patterson, Xiaoyan Li, Elise Mallon, Christopher Mcdermott, Tasnim Mushannen, Gary Pattee, Dylan Ratner, Paul Wicks, Martina Wiedau, Richard Bedlack

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2024-02-06

ALSUntangled reviews alternative and off-label treatments on behalf of people with ALS (PALS) who ask about them. Here, we review…

34

Molecular authentication, metabolite profiling and in silico-in vitro cytotoxicity screening of endophytic Penicillium ramusculum from Withania somnifera for breast cancer therapeutics

Sherin Varghese, M. S. Jisha, K. C. Rajeshkumar, Virendra Gajbhiye, Niladri Haldar, Aazam Shaikh

3 Biotech, 2024-03

In the present study, we isolated a potent endophytic fungus from the roots of Withania somnifera. The endophytic fungal strain was authenticated…

35

Ayurveda–modern medicine interface: A critical appraisal of studies of Ayurvedic medicines to treat osteoarthritis and rheumatoid arthritis

Arvind Chopra, Manjit Saluja, Girish Tillu

Journal of Ayurveda and Integrative Medicine, 2010

The potential of Ayurvedic philosophy and medicines needs to be recognized and converted into real life treatment paradigm. This article…

36

Self-care treatment for lymphoedema of lymphatic filariasis using integrative medicine

Saravu R. Narahari, Madhur G. Aggithaya, Terence J. Ryan, Kunnathody Muralidharan, Peter J. Franks, Christine Moffatt, Peter S. Mortimer

The British Journal of Dermatology, 2023-08-24

BACKGROUND: Lymphatic Filariasis (LF) is a neglected tropical disease presenting mainly as lymphoedema (elephantiasis). LF is not effectively treated. Integrative…

37

Ashwagandha- Withania somnifera (L.) Dunal as a multipotent neuroprotective remedy for genetically induced motor dysfunction and cellular toxicity in human neurodegenerative disease models of Drosophila

Mamatha Nagamadhu Murthy, Baragur Venkatanarayanasetty Shyamala

Journal of Ethnopharmacology, 2023-07-11

ETHNOPHARMACOLOGICAL RELEVANCE: Ashwagandha (Withania somnifera (L.) Dunal, well known for its multipotent therapeutic properties has been used in Ayurveda for…

38

The impact of ashwagandha on sleep quality, anxiety reduction, and stress lowering: comparative analysis of available studies

Klaudia Malec

Journal of Education, Health and Sport, 2024-01-13

Introduction and objective: The increasing prevalence of sleep disorders, anxiety, and stress in contemporary society necessitates effective and accessible treatments.…

39

SP-Max- A Herbomineral Formulation Attenuates Busulfan-Induced Oligospermia in Mice by Preventing Loss of Reproductive Hormones

Ankit P. Laddha, Shantanu Joshi, Yogesh A. Kulkarni

Reproductive Toxicology (Elmsford, N.Y.), 2023-12-18

SP-Max herbal capsule formulation contains Withania somnifera, Asparagus recemosus, Mucuna pruriens, Chlorophytum arundinaceum, Ipomoea digitata, and Dioscorea bulbifera which are…

40

Study of Drug Targets Associated With Oncogenesis and Cancer Cell Survival and the Therapeutic Activity of Engineered Ashwagandha Extract Having Differential Withanolide Constitutions

Franco Cavaleri, Sukalpa Chattopadhyay, Vrushalee Palsule, Pradip Kumar Kar, Ritam Chatterjee

Integrative Cancer Therapies, 2024

Ashwagandha (Withania somnifera) has gained worldwide popularity for a multitude of health benefits inclusive of cancer-preventive and curative effects. Despite…

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